Shopping on line can be easy, simple and save you lots of money. It can also take a lot of your time, frustrate you, and result in unwanted purchases. Now the same can be said for regular high street shopping, but with the vast opportunity presented by the Internet it will pay you to spend a few minutes reading this and understanding how to better optimize your Vaccination shopping experience:
1. Compare - without doubt the biggest advantage that the Vaccination offers shoppers today is the ability to compare thousands of Vaccination at a time. This is a great thing, but not necessarily all the time! Too much can be daunting at times so take advantage of the great comparison sites and where possible let them do the hard work for you.
2. Research - if it has been said it will be on the internet. Ignorance is no longer a justifiable reason for buying the wrong thing. Take the time to research in detail everything that you could possible want to know about
3. Testimonials - don't know anybody that has bought a Vaccination? Wrong! If the Vaccination is good the internet will let you know. Use the Internet as a friend and get testimonials before you buy.
4. Questions - Got a question about Vaccination then search the Forums, FAQ's, Blogs etc. Don't be afraid to ask .....
5. Reputation - Never heard of the company selling Vaccination? Don't worry, no reason why you should know every company in the world, but you know someone that does! Use the internet to find out what people are saying about Vaccination and build up a picture of their reputation for sales, returns, customer service, delivery etc.
6. Returns - still worried that even after all of the above your Vaccination wont be what you want? Check out the returns policy. There is so much competition now that someone, somewhere is bound to offer the terms that you are comfortable with.
7. Feedback - happy with your Vaccination then let people know, after all you are depending on others people input in your buying decision, so why not give a little back.
8. Security - check for the yellow padlock on the Vaccination site before you buy, and the s after http:/ /i.e. https:// = a secure site
9. Contact - got a question about Vaccination, or want to leave a comment then check out the sites contact page. Reputable companies have them and respond.
10. Payment - ready to pay for your Vaccination, then use your credit card or PayPal! Be aware of companies that don't accept them, there may be genuine reasons but given the huge amount of choice you have when buying online there is no reason at all not to buy via credit card or PayPal.
.
Vaccination is the administration of antigenic material to produce
immunity (medical) to a disease. This will prevent or ameliorate the effects of
infection by a
pathogen. The material administrated can either be live, but weakened forms of pathogens such as bacteria or
viruses, killed or inactivated forms of these pathogens, or purified material such as
proteins.
Smallpox was the first disease people tried to prevent by purposely inoculating themselves with other types of infections: Smallpox
inoculation was started in
India or China before 200 BC. Smithsonian National Museum of Natural History article
History of Vaccines In 1718,
Lady Mary Wortley Montague reported that the Turkey have a habit of deliberately inoculating themselves with fluid taken from mild cases of smallpox and she inoculated her own children. In 1796
Edward Jenner inoculated using cowpox (a mild relative of the deadly smallpox virus). Pasteur and others built on this. Influenza Report (free online book) chapter
Vaccines by Stephen Korsman
Benjamin Jesty is notable as perhaps the first person recorded to have vaccinated with
cowpox in order to artificially induce immunity to smallpox in the
epidemic of 1774. The term
vaccination was first used by
Edward Jenner an English physician 22 years later in 1796.
Louis Pasteur further adapted in his pioneering work in microbiology. Vaccination (Latin:
vacca—cow) is so named because the first vaccine was derived from a
virus (biology) affecting cows—the relatively benign cowpox virus—which provides a degree of immunity to
smallpox, a contagious and deadly disease. In common speech, 'vaccination' and 'immunization' generally have the same colloquial meaning. This distinguishes it from
inoculation which uses unweakened live pathogens, although in common usage either is used to refer to an
immunization. The word "vaccination" was originally used specifically to describe the injection of
smallpox vaccine. Biology-online
Vaccination efforts have been met with some anti-vaccinationists since their inception. Early success and
Vaccination Act brought widespread acceptance and mass vaccination campaigns were undertaken which have greatly reduced the incidence of many diseases in many areas. The eradication of
smallpox, which was last seen in a natural case in 1977, is considered the most spectacular success of vaccination. Currently some people assert that childhood vaccination causes some autoimmune disease and
autism. Scientific studies have not demonstrated a link, however, the assertion found space in a
United States House of Representatives report in 2003 which included the suggestion that mercury derivatives in vaccines might have been a cause of autism.{{cite web | last =Pringle
| first =Evelyn
| title = Government Investigation Finds Autism Vaccine Related
| publisher = opednews.com
| date = August 13 [
| url = http://www.opednews.com/articles/genera_evelyn_p_060813_government_investiga.htm
| accessdate = 2006-12-10-->
Triggering immune sensitization
In the generic sense, the process of
artificial induction of immunity, in an effort to protect against infectious disease, works by 'priming' the
immune system with an 'immunogen'. Stimulating immune response, via use of an infectious agent, is known as
immunization (medicine). Vaccinations involve the administration of one or more immunogens, which can be administered in several forms.
Some modern vaccines are administered after the patient already has contracted a disease, as in the cases of experimental
AIDS, cancer and Alzheimer's disease vaccines. Vaccinia given after exposure to smallpox, within the first four days, is reported to attenuate the disease considerably, and vaccination within the first week is known to be beneficial to a degree. The first
Rabies immunization was given by Louis Pasteur to a child bitten by a rabid dog, subsequently post-exposure immunization to Rabies has generally been followed by survival. The essential empiricism behind such immunizations is that the vaccine triggers an immune response more rapidly than the natural infection itself.
Most vaccines are given by hypodermic injection as they are not absorbed reliably through the gut. Live attenuated Polio, some Typhoid and Cholera Vaccines are given orally in order to produce immunity based in the bowel.
==Types of vaccinations==
All vaccinations work by presenting a foreign antigen to the immune system in order to evoke an immune response, but there are several ways to do this. The three main types are as follows:
An inactivated vaccine consists of virus particles which are grown in culture and then killed using a method such as heat or formaldehyde. The virus particles are destroyed and cannot replicate, but the virus capsid proteins are intact enough to be recognized by the immune system and evoke a response. When manufactured correctly, the vaccine is not infectious, but improper inactivation can result in intact and infectious particles. Since the properly produced vaccine does not reproduce, booster_dose shots are required periodically to reinforce the immune response.
In an attenuated vaccine, live virus particles with very low virulence are administered. They will reproduce, but very slowly. Since they do reproduce and continue to present antigen beyond the initial vaccination, boosters are required less often. These vaccines are produced by growing the virus in tissue cultures that will select for less virulent strains, or by mutagenesis or targeted deletions in genes required for virulence. There is a small risk of reversion to virulent, this risk is smaller in vaccines with deletions. Attenuated vaccines also cannot be used by immunocompromised individuals.
A subunit vaccine presents an antigen to the immune system without introducing viral particles, whole or otherwise. One method of production involves isolation of a specific protein from a virus and administering this by itself. A weakness of this technique is that isolated proteins can be denatured and will then bind to different antibodies than the proteins in the virus. A second method of subunit vaccine is the recombinant vaccine, which involves putting a protein gene from the targeted virus into another virus. The second virus will express the protein, but will not present a risk to the patient. This is the type of vaccine currently in use for hepatitis, and it is experimentally popular, being used to try to develop new vaccines for difficult to vaccinate viruses such as Ebola and HIV. Department of Veterinary Science & Microbiology at The University of Arizona Vaccines by Janet M. Decker, PhD
History of vaccinations
The origins of vaccination are surprisingly older than is commonly known. The Anatolian Ottoman Turks knew about methods of vaccination about hundred years before Edward Jenner to whom the discovery is attributed. They called vaccination Ashi or engrafting, which they used to apply to their children with cowpox taken from the breast of cattle. This kind of vaccination and other forms of variolation were introduced into England by Lady Montagu, a famous English letter-writer and wife of the English ambassador at Istanbul between 1716 and 1718. She came across the Turkish methods of vaccination, consenting to have her son inoculated by the Embassy surgeon Charles Maitland in the Turkish way. Lady Montagu wrote to her sister and friends in England describing the process in details. On her return to England she continued to propagate the Turkish tradition of vaccination and had many of her relatives inoculated. The breakthrough came when a scientific description of the vaccination operation was submitted to the Royal Society in 1724 by Dr Emmanual Timoni, who had been the Montagu’s family physician in Istanbul. Inoculation was adopted both in England and in France nearly half a century before Edward Jenner's famous smallpox vaccine of 1796. name=Anthony Henricy 1796>
Since then vaccination campaigns have spread throughout the globe, sometimes prescribed by law or regulations (See
Vaccination Acts). Vaccines are now used to fight a wide variety of disease threats besides smallpox. Louis Pasteur further developed the technique during the 19th century, extending its use to protecting against bacterial anthrax disease and viral rabies. The method Pasteur used entailed treating the infectious agents for those diseases so they lost the ability to cause serious disease. Pasteur adopted the name
vaccine as a generic term in honor of Jenner's discovery, which Pasteur's work built upon.
Prior to vaccination with cowpox, the only known protection against smallpox was
inoculation or
variolation (Variola - the Smallpox viruses) where a small amount of live smallpox virus was administered to the patient; this carried the serious risk that the patient would be killed or seriously ill. The death rate from variolation was reported to be around a tenth of that from natural infection with Variola, and the immunity provided was considered quite reliable. Factors contributing to the efficacy of variolation probably include the choices of Variola Minor strains used, the relatively low number of cells infected in the first phase of multiplication following initial exposure, and the exposure route used, via the skin or nasal lining rather than inhalation of droplets into the lungs.
Consistency would suggest the activity should have predated Jenner's description of an effective vaccination system, and there is some history relating to opposition to the older and more hazardous procedure of variolation.
In modern times, the first vaccine-preventable disease targeted for eradication was smallpox. The World Health Organization coordinated the global effort to eradicate this disease. The last naturally occurring case of smallpox occurred in Somalia in 1977.
In 1988, the governing body of W.H.O. targeted
Polio eradication by the year 2000. Although the target was missed, eradication is very close. The next eradication target would most likely be measles, which has declined since the introduction of measles vaccination in 1963.
In 2000, the
Global Alliance for Vaccines and Immunization was established to strengthen routine vaccinations and introduce new and under-used vaccines in countries with a per capita GDP of under US$1000. GAVI is now entering its second phase of funding, which extends through 2014.
Vaccination policies, compulsory vaccination
In an attempt to eliminate the risk of outbreaks of some diseases, at various times several governments and other institutions have instituted policies requiring vaccination for all people. For example, an 1853 law required universal vaccination against smallpox in
England and
Wales, with fines levied on people who did not comply. Common contemporary U.S. vaccination policies require that children receive common vaccinations before entering school. A few other countries also have some compulsory vaccinations.
Beginning with early vaccination in the nineteenth century, these policies led to resistance from a variety of groups, collectively called anti-vaccinationists, who objected on ethical, political, medical safety,
vaccination and religion, and other grounds. Common objections are that compulsory vaccination represents excessive government intervention in personal matters, or that the proposed vaccinations are not sufficiently safe. Many modern vaccination policies allow exemptions for people who have compromised immune systems, allergies to the components used in vaccinations or strongly-held objections.Salmon, Daniel A
et al. (2006) Compulsory vaccination and conscientious or philosophical exemptions: past, present, and future.
The Lancet 367(9508):436-442.
Herd immunity and medical risk management issues
Vaccination campaigns are generally accepted as having contributed to the worldwide elimination of
smallpox, through herd immunity, and to the restriction of
polio to isolated pockets in countries where healthcare access is difficult. The
risk management practices of government health agencies' promoting widespread vaccination campaigns has prompted increasing controversy in recent years, despite the fact that many once-common childhood diseases, such as mumps, measles and rubella, are now relatively rare in developed countries.
Adjuvants and preservatives
Vaccines typically contain one or more
adjuvants, used to boost the immune response.Tetanus toxoid for instance is usually adsorbed onto Alum. This presents the antigen in such a way as to produce a greater action than the simple aqueous tetanus toxoid. People who get an excessive reaction to adsorbed tetanus toxoid may be given the simple vaccine when time for a booster occurs.
In the preparation for the 1990 Gulf campaign, Pertussis vaccine (not acellular) was used as an adjuvant for Anthrax vaccine. This produces a more rapid immune response than giving only the Anthrax, which is of some benefit if exposure might be imminent.
They may also contain preservatives, which are used to prevent contamination with bacteria or fungi. Until recent years, the preservative
thiomersal was used in many vaccines that did not contain live virus.
As of 2005, the only childhood vaccine in the U.S.A. that contains thiomerosal is the influenza vaccine , which is currently recommended only for children with certain risk factors.Melinda Wharton. National Vaccine Advisory committee U.S.A. national vaccine plan The UK is considering Influenza immunisation in children perhaps as soon as in 2006-7. Single-dose Influenza vaccines supplied in the UK do not list Thiomersal (its UK name) in the ingredients. Preservatives may be used at various stages of production of vaccines, and the most sophisticated methods of measurement might detect traces of them in the finished product, as they may in the environment and population as a whole.
Combined vaccines
Combined vaccinations are now widely used around the world, a result of the rapid increase in the number of shots recommended in current
vaccination schedules.
Methods of administration
A vaccine administration may be oral, by injection, intravenously, by puncture, transdermal or intranasal.{{cite book| last = Plotkin| first = Stanley A.| title = Mass Vaccination: Global Aspects - Progress and Obstacles (Current Topics in Microbiology & Immunology)| publisher = Springer-Verlag Berlin and Heidelberg GmbH & Co. K| date = 2006| isbn = 978-3540293828-->
Vaccine research
Some major contemporary research in vaccination focuses on development of vaccinations for diseases including HIV vaccine and malaria.
Vaccine is an international
peer-reviewed journal for vaccination researchers, indexed in Medline pISSN: 0264-410X.
See also
References
External links
- The Vaccine Page links to resources in many countries.
- Immunisation Immunisation schedule for children in the UK. Published by the UK Department of Health.
- Vaccine Ingredients A list of vaccine ingredients.
- Brian Deer.com - 'mmr & autism investigation: part 1: the Lancet scandal', Brian Deer
- CDC.gov - 'National Immunization Program: leading the way to healthy lives', Centers for Disease Control (CDC information on vaccinations)
- CDC.gov - 'Mercury and Vaccines (Thimerosal)', US Centers for Disease Control
- Immunize.org - Immunization Action Coalition' (nonprofit working to increase immunization rates)
- NYTimes.com - 'On Autism's Cause, It's Parents vs. Research', Gardiner Harris, Anahad O'Connor, New York Times (front page; June 25, 2005)
- OpinionJournal.com - 'Autism and vaccines: Activists wage a nasty campaign to silence scientists' (unsigned editorial opinion), Wall Street Journal (February 16, 2004)
- SNHS.com - 'Anti-vaccine activists get jabbed', Michael Fumento (March 11, 2004)
- WHO.int - 'Immunizations, vaccines and biologicals: Towards a World free of Vaccine Preventable Diseases', World Health Organization (WHO's global vaccination campaign website)
- 909Shot.com - 'National Vaccine Information Center: the oldest and largest national organization advocating reformation of the mass vaccination system'
- VaccinationDebate.com - 'Vaccination Debate', Ian Sinclair
- VacLib.org - 'Vaccination Liberation'
.
Vaccination is the administration of antigenic material to produce immunity (medical) to a disease. This will prevent or ameliorate the effects of infection by a
pathogen. The material administrated can either be live, but weakened forms of pathogens such as bacteria or viruses, killed or inactivated forms of these pathogens, or purified material such as
proteins. Smallpox was the first disease people tried to prevent by purposely inoculating themselves with other types of infections: Smallpox inoculation was started in India or
China before 200 BC. Smithsonian National Museum of Natural History article
History of Vaccines In 1718,
Lady Mary Wortley Montague reported that the Turkey have a habit of deliberately inoculating themselves with fluid taken from mild cases of smallpox and she inoculated her own children. In 1796
Edward Jenner inoculated using
cowpox (a mild relative of the deadly smallpox virus).
Pasteur and others built on this. Influenza Report (free online book) chapter
Vaccines by Stephen Korsman
Benjamin Jesty is notable as perhaps the first person recorded to have vaccinated with
cowpox in order to artificially induce immunity to
smallpox in the
epidemic of 1774. The term
vaccination was first used by Edward Jenner an English physician 22 years later in 1796.
Louis Pasteur further adapted in his pioneering work in microbiology. Vaccination (
Latin:
vacca—cow) is so named because the first vaccine was derived from a
virus (biology) affecting cows—the relatively benign cowpox virus—which provides a degree of immunity to
smallpox, a contagious and deadly disease. In common speech, 'vaccination' and 'immunization' generally have the same colloquial meaning. This distinguishes it from
inoculation which uses unweakened live pathogens, although in common usage either is used to refer to an immunization. The word "vaccination" was originally used specifically to describe the injection of
smallpox vaccine. Biology-online
Vaccination efforts have been met with some anti-vaccinationists since their inception. Early success and
Vaccination Act brought widespread acceptance and mass vaccination campaigns were undertaken which have greatly reduced the incidence of many diseases in many areas. The eradication of smallpox, which was last seen in a natural case in 1977, is considered the most spectacular success of vaccination. Currently some people assert that childhood vaccination causes some
autoimmune disease and autism. Scientific studies have not demonstrated a link, however, the assertion found space in a
United States House of Representatives report in 2003 which included the suggestion that mercury derivatives in vaccines might have been a cause of autism.{{cite web | last =Pringle
| first =Evelyn
| title = Government Investigation Finds Autism Vaccine Related
| publisher = opednews.com
| date = August 13 [
| url = http://www.opednews.com/articles/genera_evelyn_p_060813_government_investiga.htm
| accessdate = 2006-12-10-->
Triggering immune sensitization
In the generic sense, the process of artificial induction of immunity, in an effort to protect against
infectious disease, works by 'priming' the immune system with an 'immunogen'. Stimulating immune response, via use of an infectious agent, is known as
immunization (medicine). Vaccinations involve the administration of one or more immunogens, which can be administered in several forms.
Some modern vaccines are administered after the patient already has contracted a disease, as in the cases of experimental AIDS, cancer and Alzheimer's disease vaccines. Vaccinia given after exposure to smallpox, within the first four days, is reported to attenuate the disease considerably, and vaccination within the first week is known to be beneficial to a degree. The first Rabies immunization was given by
Louis Pasteur to a child bitten by a rabid dog, subsequently post-exposure immunization to Rabies has generally been followed by survival. The essential empiricism behind such immunizations is that the vaccine triggers an immune response more rapidly than the natural infection itself.
Most vaccines are given by hypodermic injection as they are not absorbed reliably through the gut. Live attenuated Polio, some Typhoid and Cholera Vaccines are given orally in order to produce immunity based in the bowel.
==Types of vaccinations==
All vaccinations work by presenting a foreign antigen to the immune system in order to evoke an immune response, but there are several ways to do this. The three main types are as follows:
An inactivated vaccine consists of virus particles which are grown in culture and then killed using a method such as heat or formaldehyde. The virus particles are destroyed and cannot replicate, but the virus capsid proteins are intact enough to be recognized by the immune system and evoke a response. When manufactured correctly, the vaccine is not infectious, but improper inactivation can result in intact and infectious particles. Since the properly produced vaccine does not reproduce, booster_dose shots are required periodically to reinforce the immune response.
In an attenuated vaccine, live virus particles with very low virulence are administered. They will reproduce, but very slowly. Since they do reproduce and continue to present antigen beyond the initial vaccination, boosters are required less often. These vaccines are produced by growing the virus in tissue cultures that will select for less virulent strains, or by mutagenesis or targeted deletions in genes required for virulence. There is a small risk of reversion to virulent, this risk is smaller in vaccines with deletions. Attenuated vaccines also cannot be used by immunocompromised individuals.
A subunit vaccine presents an antigen to the immune system without introducing viral particles, whole or otherwise. One method of production involves isolation of a specific protein from a virus and administering this by itself. A weakness of this technique is that isolated proteins can be denatured and will then bind to different antibodies than the proteins in the virus. A second method of subunit vaccine is the recombinant vaccine, which involves putting a protein gene from the targeted virus into another virus. The second virus will express the protein, but will not present a risk to the patient. This is the type of vaccine currently in use for hepatitis, and it is experimentally popular, being used to try to develop new vaccines for difficult to vaccinate viruses such as Ebola and HIV. Department of Veterinary Science & Microbiology at The University of Arizona Vaccines by Janet M. Decker, PhD
History of vaccinations
The origins of vaccination are surprisingly older than is commonly known. The Anatolian Ottoman Turks knew about methods of vaccination about hundred years before Edward Jenner to whom the discovery is attributed. They called vaccination Ashi or engrafting, which they used to apply to their children with cowpox taken from the breast of cattle. This kind of vaccination and other forms of variolation were introduced into England by Lady Montagu, a famous English letter-writer and wife of the English ambassador at Istanbul between 1716 and 1718. She came across the Turkish methods of vaccination, consenting to have her son inoculated by the Embassy surgeon Charles Maitland in the Turkish way. Lady Montagu wrote to her sister and friends in England describing the process in details. On her return to England she continued to propagate the Turkish tradition of vaccination and had many of her relatives inoculated. The breakthrough came when a scientific description of the vaccination operation was submitted to the Royal Society in 1724 by Dr Emmanual Timoni, who had been the Montagu’s family physician in Istanbul. Inoculation was adopted both in England and in France nearly half a century before
Edward Jenner's famous smallpox vaccine of 1796. name=Anthony Henricy 1796>
Since then vaccination campaigns have spread throughout the globe, sometimes prescribed by law or regulations (See Vaccination Acts). Vaccines are now used to fight a wide variety of disease threats besides
smallpox.
Louis Pasteur further developed the technique during the 19th century, extending its use to protecting against bacterial
anthrax disease and viral rabies. The method Pasteur used entailed treating the infectious agents for those diseases so they lost the ability to cause serious disease. Pasteur adopted the name
vaccine as a generic term in honor of Jenner's discovery, which Pasteur's work built upon.
Prior to vaccination with cowpox, the only known protection against smallpox was
inoculation or
variolation (Variola - the Smallpox viruses) where a small amount of live smallpox virus was administered to the patient; this carried the serious risk that the patient would be killed or seriously ill. The death rate from variolation was reported to be around a tenth of that from natural infection with Variola, and the immunity provided was considered quite reliable. Factors contributing to the efficacy of variolation probably include the choices of Variola Minor strains used, the relatively low number of cells infected in the first phase of multiplication following initial exposure, and the exposure route used, via the skin or nasal lining rather than inhalation of droplets into the lungs.
Consistency would suggest the activity should have predated Jenner's description of an effective vaccination system, and there is some history relating to opposition to the older and more hazardous procedure of variolation.
In modern times, the first vaccine-preventable disease targeted for eradication was smallpox. The World Health Organization coordinated the global effort to eradicate this disease. The last naturally occurring case of smallpox occurred in Somalia in 1977.
In 1988, the governing body of W.H.O. targeted Polio eradication by the year 2000. Although the target was missed, eradication is very close. The next eradication target would most likely be measles, which has declined since the introduction of measles vaccination in 1963.
In 2000, the
Global Alliance for Vaccines and Immunization was established to strengthen routine vaccinations and introduce new and under-used vaccines in countries with a per capita GDP of under US$1000. GAVI is now entering its second phase of funding, which extends through 2014.
Vaccination policies, compulsory vaccination
In an attempt to eliminate the risk of outbreaks of some diseases, at various times several governments and other institutions have instituted policies requiring vaccination for all people. For example, an 1853 law required universal vaccination against smallpox in
England and Wales, with fines levied on people who did not comply. Common contemporary U.S. vaccination policies require that children receive common vaccinations before entering school. A few other countries also have some compulsory vaccinations.
Beginning with early vaccination in the nineteenth century, these policies led to resistance from a variety of groups, collectively called
anti-vaccinationists, who objected on ethical, political, medical safety, vaccination and religion, and other grounds. Common objections are that compulsory vaccination represents excessive government intervention in personal matters, or that the proposed vaccinations are not sufficiently safe. Many modern vaccination policies allow exemptions for people who have compromised immune systems, allergies to the components used in vaccinations or strongly-held objections.Salmon, Daniel A
et al. (2006) Compulsory vaccination and conscientious or philosophical exemptions: past, present, and future.
The Lancet 367(9508):436-442.
Herd immunity and medical risk management issues
Vaccination campaigns are generally accepted as having contributed to the worldwide elimination of smallpox, through herd immunity, and to the restriction of polio to isolated pockets in countries where healthcare access is difficult. The
risk management practices of government health agencies' promoting widespread vaccination campaigns has prompted increasing controversy in recent years, despite the fact that many once-common childhood diseases, such as
mumps, measles and
rubella, are now relatively rare in developed countries.
Adjuvants and preservatives
Vaccines typically contain one or more
adjuvants, used to boost the immune response.Tetanus toxoid for instance is usually adsorbed onto Alum. This presents the antigen in such a way as to produce a greater action than the simple aqueous tetanus toxoid. People who get an excessive reaction to adsorbed tetanus toxoid may be given the simple vaccine when time for a booster occurs.
In the preparation for the 1990 Gulf campaign, Pertussis vaccine (not acellular) was used as an adjuvant for Anthrax vaccine. This produces a more rapid immune response than giving only the Anthrax, which is of some benefit if exposure might be imminent.
They may also contain preservatives, which are used to prevent contamination with bacteria or
fungi. Until recent years, the preservative
thiomersal was used in many vaccines that did not contain live virus. As of 2005, the only childhood vaccine in the U.S.A. that contains thiomerosal is the influenza vaccine , which is currently recommended only for children with certain risk factors.Melinda Wharton. National Vaccine Advisory committee U.S.A. national vaccine plan The UK is considering Influenza immunisation in children perhaps as soon as in 2006-7. Single-dose Influenza vaccines supplied in the UK do not list Thiomersal (its UK name) in the ingredients. Preservatives may be used at various stages of production of vaccines, and the most sophisticated methods of measurement might detect traces of them in the finished product, as they may in the environment and population as a whole.
Combined vaccines
Combined vaccinations are now widely used around the world, a result of the rapid increase in the number of shots recommended in current
vaccination schedules.
Methods of administration
A vaccine administration may be oral, by injection, intravenously, by puncture, transdermal or intranasal.{{cite book| last = Plotkin| first = Stanley A.| title = Mass Vaccination: Global Aspects - Progress and Obstacles (Current Topics in Microbiology & Immunology)| publisher = Springer-Verlag Berlin and Heidelberg GmbH & Co. K| date = 2006| isbn = 978-3540293828-->
Vaccine research
Some major contemporary research in vaccination focuses on development of vaccinations for diseases including HIV vaccine and malaria.
Vaccine is an international peer-reviewed journal for vaccination researchers, indexed in
Medline pISSN: 0264-410X.
See also
References
External links
- The Vaccine Page links to resources in many countries.
- Immunisation Immunisation schedule for children in the UK. Published by the UK Department of Health.
- Vaccine Ingredients A list of vaccine ingredients.
- Brian Deer.com - 'mmr & autism investigation: part 1: the Lancet scandal', Brian Deer
- CDC.gov - 'National Immunization Program: leading the way to healthy lives', Centers for Disease Control (CDC information on vaccinations)
- CDC.gov - 'Mercury and Vaccines (Thimerosal)', US Centers for Disease Control
- Immunize.org - Immunization Action Coalition' (nonprofit working to increase immunization rates)
- NYTimes.com - 'On Autism's Cause, It's Parents vs. Research', Gardiner Harris, Anahad O'Connor, New York Times (front page; June 25, 2005)
- OpinionJournal.com - 'Autism and vaccines: Activists wage a nasty campaign to silence scientists' (unsigned editorial opinion), Wall Street Journal (February 16, 2004)
- SNHS.com - 'Anti-vaccine activists get jabbed', Michael Fumento (March 11, 2004)
- WHO.int - 'Immunizations, vaccines and biologicals: Towards a World free of Vaccine Preventable Diseases', World Health Organization (WHO's global vaccination campaign website)
- 909Shot.com - 'National Vaccine Information Center: the oldest and largest national organization advocating reformation of the mass vaccination system'
- VaccinationDebate.com - 'Vaccination Debate', Ian Sinclair
- VacLib.org - 'Vaccination Liberation'
www.vaccination.co.uk > Home ( DNN 3.1.1 )
This tries to help by giving simple facts about the different diseases, their corresponding vaccines / vaccinations and the risks attached to both, places to find guidance and ...
Vaccination
Vaccination at vaccination.co.uk tries to help, in the decision making process that comes with having vaccinations, by giving information, places to find guidance and allow you to ...
Vaccination - Wikipedia, the free encyclopedia
Vaccination is the administration of antigenic material (the vaccine) to produce immunity to a disease. Vaccines can prevent or ameliorate the effects of infection by a pathogen.
Future of Vaccination
The latest news and top stories from Intervet UK regarding pet vaccination issues and the latest vaccine information for your dog, cat, puppy or kitten.
Medical Glossary - NHS Direct
Vaccination Vaccination or immunisation is usually given by an injection that makes the body's immune system produce antibodies that will fight off a virus.
Pet Vaccination Clinic - Main Home Page
Pet Vaccination Clinic provides high quality veterinary care at the lowest possible prices. We have clinics in Coventry, Nuneaton, Stechford and Wythall.
HPV vaccination Introduction - Health encyclopaedia - NHS Direct
Human papilloma virus vaccination programme ... The Department of Health has agreed to introduce the human papilloma virus (HPV) vaccination for girls who are between12-13 years of ...
Definition: vaccination from Online Medical Dictionary
The Online Medical Dictionary is a searchable dictionary of definitions from medicine, science and technology.
Flu vaccination, prevention & treatment | Flu Jabs | Flu Jab
Flu Vaccination, Flu Jabs and Company Flu Vaccination, by appointment and on a walk-in or call-out basis for everyone who wants protection throughout the flu vaccination season.
Vaccination Chart
The following chart gives some idea of how often boosters should be administered according to the UK Guidelines.